Moderate exercise good; exhaustive exercise bad. Who knew?

Man down!

This bit of wisdom is from a peer-reviewed scientific journal,  Free Radical Biology & Medicine:

Free radicals in exhaustive physical exercise

The beneficial effects of regular, nonexhaustive physical exercise have been known for a long time. There is irrefutable evidence of the effectiveness of regular physical activity in the primary and secondary prevention of several chronic diseases (e.g., cardiovascular disease, diabetes, cancer, hypertension, obesity, depression, and osteoporosis) and premature death. However, the beneficial effects of exercise are lost with exhaustion. It is well known that exhaustive exercise (especially when sporadic) causes structural damage to muscle cells or inflammatory reactions within the muscles, for instance, as evidenced by an increase in the plasma activity of cytosolic enzymes and sarcolemma and Z-line disruption.

Full article: Moderate exercise is an antioxidant